
一、基本信息
高晓娜,女,博士,硕士研究生导师,江西农业大学副教授。2021年毕业于南京农业大学,读博期间曾到美国威斯康星大学麦迪逊分校访学。现为中国畜牧兽医学会兽医内科与临床诊疗学分会理事、中国畜牧兽医学会兽医外科学分会理事、江西省科技特派员,江西省家禽产业技术体系首席专家团队骨干成员,江西省遂川肉鸽科技小院和江西省大余麻鸭科技小院指导专家。Poultry science、Journal of nutritional biochemistry等SCI杂志审稿专家。主要从事畜禽营养代谢病的发病机理和防控方法研究。
E-mail: xiaona.gao@jxau.edu.cn。
二、科研项目概况
先后主持国家自然科学基金项目2项、国家重点研发计划课题1项,江西省自然科学基金1项、江西省教改课题1项,江西省教育厅科技项目2项、横向项目1项,并参与多项国家自然科学基金、省自然科学基金及横向课题。指导国家级创新创业项目1项、江西省创新创业项目3项。2022年被评为江西农业大学先进工作者。先后发表学术论文40余篇,其中SCI收录30余篇。
三、教育经历(按时间倒序)
[1] 2017-09至2021-06,南京农业大学,临床兽医学,博士
[2] 2014-09至2017-06,江西农业大学,临床兽医学,硕士
[3] 2010-09至2014-06,青岛农业大学,动物医学,学士
四、工作经历(按时间倒序)
2021.10-2024.12,江西农业大学,动物科学技术学院,讲师;
2024.12-至今,江西农业大学,动物科学技术学院,副教授。
五、代表性研究成果和学术奖励情况
(一)代表性 SCI 学术论文(近五年优先,按时间降序)
1.Huang C#, Zeng Y#, Chen Y#, Li Z, Omar SM, Zhong S, Liu P, Zheng Z, Cai G, Gao X*, Guo X*. NIBV Induces Incomplete Autophagy via AMPK-TFEB, Causing Kidney Injury in Chicks. Adv Sci (Weinh). 2026 Jun;13(34):e14993.
2.Luo J#, Shi Y, Jiang X, Zhang B, Chen Y, Liu L, Liu P, Cai G, Zheng Z, Guo X, Gao X*. Preparation of a polyclonal antibody against Lysosome-Associated Membrane Protein-1 for chicken and its application in the liver of broilers under chronic heat stress. Int J Biol Macromol. 2026 Apr;354:151401.
3.Liao K#, Wang L, Luo J, Jiang X, Zhou S, Li F, Liu P, Cai G, Zheng Z, Guo X, Gao X*. Naringenin alleviates heat stress-induced thymic injury through a triple mechanism of immune modulation, antioxidant defense, and inflammation suppression. Poult Sci. 2026 Jul;105(7):106925.
4.Fang J#, Jiang Z, Luo J, Wang S, Guo X, Liu P, Zheng Z, Cai G, Gao X*. Naringenin ameliorates heat-stress-induced heart injury by regulating ferroptosis and ferritinophagy in chickens. J Nutr Biochem. 2026 Sep;155:110364.
5.Lin S, Shi Y, Liu J, Luo J, Liao K, Liu P, Gao, X*. Gut microbiome and metabolome analysis reveal the alleviating effect of naringenin on duodenal damage in Ningdu yellow chickens caused by heat stress. Avian Pathol. 2026 Feb;55(1):64-78.
6.Liu Z#, Tang R#, Ding M, Wu M, Li Y, Huang C, Qi Q, Liu P, Gao, X*, Guo X*. Cepharanthine mitigates NIBV-induced pyroptosis via the MDA5/NF-κB/NLRP3 signaling pathway. Vet Microbiol, 2025 Jun; 305:110519.
7.Liu Z#, Tang R#, Qi Q, Lin S, Liu P, Cai G, Zheng Z, Guo, X*, Gao, X* (Gao Xiaona). Naringenin alleviates heat stress-induced liver injury in Ningdu yellow chickens by decreasing RIPK3 and PDC binding. J Nutr Biochem. 2025 Jun;140:109894.
8.Li Z, Zhang B, Shen Y, Liu P, Shi Y, Cai G, Zheng Z, Gao X*, Guo X*. Morphological Immunological and Genetic Studies in The Bursa of Fabricius in Nephropathogenic Infectious Bronchitis Virus-Induced Inflammation Via the MDA5/IPS-1 Signaling Axis. Pakistan Veterinary Journal. 2025; 45(3):1226-1234.
9.Du J, Li Z, Cao X, Qi Q, Wang L, Liu P, Chen Y, Hu G, Guo X*, Gao X*. Mechanism of Mitochondrial Kinetic Imbalance and Nrf2 Signaling Pathway-Mediated Oxidative Stress in Nickel and/or Chromium-Induced Kidney Injury in Mice. Antioxidants (Basel). 2024 Aug 13;13(8):980.
10.Chen W#, Huang C#, Shi Y, Li N, Wang E, Hu R, Li G, Yang F, Zhuang Y, Liu P, Hu G, Gao X*, Guo X*, Investigation of the Crosstalk between GRP78/PERK/ATF-4 Signaling Pathway and Renal Apoptosis Induced by Nephropathogenic Infectious Bronchitis Virus Infection. J Virol, 2022. 96(2): p. e0142921.
11.Li Q#, Fang W#, Chen S, Li G, Jiang C, Zhuang Y, Li L, Liu P, Guo X, Hu G, Liu P, Gao X*. Characterization of Escherichia coli pathogenicity and drug resistance in yolk peritonitis. Poult Sci. 2024 Apr 27;103(7):103814.
12.Cao X#, Zheng S#, Zeng Y, Shi Y, Du J, Huang C, Shen Y, Liu P, Guo X, Gao X*. Effects of chronic Cr and Ni co-exposure on liver inflammation and autophagy in mice by regulating the TLR4/mTOR pathway. Sci Total Environ. 2024 May 20;926:171921.
13.Chen Y#, Feng C#, Huang C, Shi Y, Omar SM, Zhang B, Cai G, Liu P, Guo X*, Gao X*. Preparation of polyclonal antibodies to chicken P62 protein and its application in nephropathogenic infectious bronchitis virus-infected chickens. Int J Biol Macromol. 2024 May 18;271(Pt 2):132515.
14.Zeng Y#, Shi Y#, Chen Y, Zhong S, Omar SM, Liu P, Zhuang Y, Cai G, Guo X*, Gao X*. Preparation of polyclonal antibody to CHOP protein and its application in heat stress of chickens. Int J Biol Macromol. 2025 Jan;286:138362.
15.Tian G#, Shi Y#, Cao X, Chen W, Gu Y, Li N, Huang C, Zhuang Y, Li G, Liu P, Hu G, Gao X*, Guo X, Preparation of the RIPK3 Polyclonal Antibody and Its Application in Immunoassays of Nephropathogenic Infectious Bronchitis Virus-Infected Chickens. Viruses, 2022. 14(8).
16.Tian G#, Huang C, Li Z, Lu Z, Feng C, Zhuang Y, Li G, Liu P, Hu G, Gao X*, Guo X*. Baicalin mitigates nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line chick. Vet Microbiol. 2023 Nov;286:109891.
17.Li N#, Huang C#, Chen W, Li Z, Hu G, Li G, Liu P, Hu R, Zhuang Y, Luo J, Gao X*, Guo X*. Nephropathogenic Infectious Bronchitis Virus Mediates Kidney Injury in Chickens via the TLR7/NF-κB Signaling Axis. Front Cell Infect Microbiol. 2022 Mar; 23:12:865283.
18.Chen W#, Huang C#, Shi Y, Li N, Wang E, Hu R, Li G, Yang F, Zhuang Y, Liu P, Hu G, Gao X*, Guo X*. Investigation of the Crosstalk between GRP78/PERK/ATF-4 Signaling Pathway and Renal Apoptosis Induced by Nephropathogenic Infectious Bronchitis Virus Infection. J Virol. 2022 Jan 26;96(2):e0142921.
19.Gao X#, Liu S#, Tan L, Ding C, Fan W, Gao Z, Li M, Tang Z, Wu Y, Xu L, Yan L, Luo Y, Song S*, Estrogen Receptor alpha Regulates Metabolic-Associated Fatty Liver Disease by Targeting NLRP3-GSDMD Axis-Mediated Hepatocyte Pyroptosis. J Agric Food Chem, 2021. 69(48): p. 14544-14556.
20.Gao X.#, Liu S., Ding C., Miao Y., Gao Z., Li M., Fan W., Tang Z., Mhlambi N. H., Yan L., Song S. *, Comparative effects of genistein and bisphenol A on non-alcoholic fatty liver disease in laying hens. Environ Pollut, 2021. 288: p. 117795.
21.Gao X#, Fan W, Tan L, Shi Y, Ding C, Liu S, Miao Y, Luo Y, Shi X, Desaeger S., Song S*, Soy isoflavones ameliorate experimental colitis by targeting ERalpha/NLRP3 inflammasome pathways. J Nutr Biochem, 2020. 83: p. 108438 .
22.Gao X#, Liu P #, Wu C, Wang T, Liu G, Cao H, Zhang C, Hu G*, Guo X*, Effects of fatty liver hemorrhagic syndrome on the AMP-activated protein kinase signaling pathway in laying hens. Poult Sci, 2019. 98(5): p. 2201-2210 DOI: 10.3382/ps/pey586.
23.Huang Q.#, Gao X.#, Liu P.#, Lin H., Liu W., Liu G., Zhang J., Deng G., Zhang C., Cao H., Guo X.*, Hu G.*, The relationship between liver-kidney impairment and viral load after nephropathogenic infectious bronchitis virus infection in embryonic chickens. Poult Sci, 2017. 96(6): p. 1589-1597 DOI: 10.3382/ps/pew455.
(二)发明专利
1. 高晓娜、郭小权、施燕、刘平、胡国良、庄煜、蔡高峰、郑展宏、林思婷、刘璟,Additive for Resisting Heat Stress of Poultry,专利号:FPTNC202413203。
2. 郭小权、施燕、田官明、胡国良、高晓娜、刘平、庄煜、黄橙、李谷月、操贤洪、陈卫、顾玥明、李宁,鸡RIPK3基因多克隆抗体及其制备方法与应用,专利号:ZL 2021 1 1564008.7。
3. 郭小权、蔡高峰、陈其杰、高晓娜、刘平、郑展宏、李谷月,山香圆叶超微粉在制备防鸭疫里默氏杆菌病产品中的应用,专利号:ZL 2025 1 1181662.8。
4. 吴欢生、谢华丽、曾庆华、胡煜、陈政、郭小权、高晓娜、庄煜、潘航、谢霜、宋德平,传染性法氏囊病病毒VP3磷酸化缺失病毒、构建方法以及其应用,专利号:ZL 2024 1 1877933.9。
5. 张磊、姜树林、丁廣森、万乐音、高晓娜、余晨琦、曾艳兵、谢淑荣,基于蛋鸡养殖的环境健康分析方法及系统专利号:ZL 2025 1 1803659.5。
(三)学术奖励情况
1.“3-2-1”三维融合:科技特派员任务驱动兽医研究生培养体系创新与实践,江西省教学成果二等奖,(2026年,排名第6)。
2.“课程筑本、载体赋能、劳创融合”三层递进式动物医学专业育人新模式的构建与实践,江西农业大学教学成果一等奖,(2026年,排名第6)。
六、主持或参加科研项目及人才计划项目情况(时间倒序)
[1]国家自然科学基金地区项目:PLIN2-LIPA介导的脂噬在热应激致鸡肝脏脂肪变性中的作用(32560883),2026.01-2029.12,32万,在研,主持;
[2] 国家重点研发计划子课题:畜禽群发普通病防控技术研发与应用-2(2023YFD1801100),2023.12-2027.12,25万,已结题,主持;
[3] 国家自然科学基金青年项目:热应激干扰PPARγ-NLRP3信号轴致三黄鸡肠道黏膜屏障功能损伤的机制及染料木素的保护作用(32202880),2023.01-2025.12,30万,已结题,主持;
[3]江西省自然科学基金青年基金:柚皮素激活PPARα介导的线粒体动力学缓解热应激导致肠道屏障损伤的机制(20224BAB215056), 2023.01-2025.12,10万元, 已结题,主持;
[4] 江西省教育厅科技计划项目重点项目:肉鸽的几种主要病原性疾病的同步快速分子诊断方法的建立与应用(GJJ2200407), 2023.01-2025.12,5万元,已结题,主持;
[5] 江西省教育厅教改课题:线上线下混合课堂模式下兽医产科学教学改革与实践(JXJG-22-3-15),2023.01-2024.12,2万元, 已结题,主持;
[6] 江西省教育厅, 江西省教育厅科技计划项目,染料木素通过调控Muc2对禽大肠杆菌致肠炎的保护机制研究(GJJ210415), 2022.01- 2024.12,3万元,已结题,主持;
[7] 江西农业大学人才引进启动项目,30万,在研,主持。